The Irish edged the Tigers by a score of 36-34. Over the course of their last three meetings, Ursuline has defeated Massillon by a total of 13 points.
Ryan Strollo led the way for Ursuline with 13 points. Jalen Lowe added 11 points and 9 rebounds.
Ursuline improves to 6-2 after prevailing in five of their last six outings. The Fighting Irish will play host to Bedford on Tuesday.
Since beginning the campaign with a 3-0 mark, Massillon has lost their last five games.