Katie Santor's three-pointer late in the game sealed the victory for Jackson-Milton as the Blue Jays defeated Mathews 52-47.
Jackson-Milton needed to rally from a one point deficit in the fourth quarter to earn the victory.
Maggie Oblinger and Maddie Tomaino also had key baskets in the final quarter to help the Blue Jays.
Oblinger finished with 10 points. Paije Kiraly added nine points while Santor led the Blue Jays with 14.
Mathews used a 21-2 run between the third and fourth quarters to take a brief one-point lead.
Jackie Rhine's jumper capped the rally. She had 12 points. Dajna Ellis had a big third quarter for the Mustangs as well, finishing with a game-high 17 points.